Does scoliosis has a bad effect in processing canada work permit?

In cases in which a medical examination is a requirement, determination of medical admissibility is made by a Medical Officer in consideration of all available information. It is not possible to absolutely determine this in advance.

If a condition does not pose a threat of excessive demand of the Canadian health-care system, and does not affect employ-ability in your field, then it should not be grounds for inadmissibility.